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NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes.
The effect of inhibition of NADP-specific isocitrate dehydrogenase (EC 1.1.1.42) by DL-threo-alpha-methylisocitrate (3-hydroxy-1,2,3-butanetricarboxylase) on urea synthesis was studied in isolated rat hepatocytes. alpha-Methylisocitrate substantially inhibited the rate of urea synthesis (35--84%) wi...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
1980
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1162135/ https://ncbi.nlm.nih.gov/pubmed/7470071 |
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