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Inhibition of glutamine synthetase activity by manganous ions in a cytosol extract of rat liver.

Glutamine synthetase activity in a cytosol extract of liver was inhibited non-competitively by Mn2+ ions. The apparent Ki for Mn2" in the presence of phosphate was 8 micro M. Inhibition of glutamine synthetase by intracellular Mn2+ may contribute to the very low rates of glutamine synthesis obs...

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Библиографические подробности
Главные авторы: Joseph, S K, Bradford, N M, McGivan, J D
Формат: Artigo
Язык:Inglês
Опубликовано: 1979
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1161787/
https://ncbi.nlm.nih.gov/pubmed/43147
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