Cell-free conversion of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremonium.

Cell-free extracts of antibiotic-negative mutants of Cephalosporium acremonium converted delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine (LLD-tripeptide) into an antibiotic that was destroyed by penicillinase. The enzymic activity of the extracts was destroyed by boiling, but was not inhibited by c...

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Detalhes bibliográficos
Main Authors: Konomi, T, Herchen, S, Baldwin, J E, Yoshida, M, Hunt, N A, Demain, A L
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1161778/
https://ncbi.nlm.nih.gov/pubmed/575041
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