Inhibition by trioxalen (psoralen) plus near-ultraviolet light of the induction of ornithine decarboxylase in Chinese-hamster cells.

Trioxalen (trimethylpsoralen) plus near-u.v. light, a potent inhibitor of DNA and RNA synthesis, inhibits the induction of ornithine decarboxylase in stationary-phase V79 fibroblasts. It does not affect the translation of pre-existing mRNA. The method, in view of its high degree of specificity and p...

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Bibliographic Details
Main Authors: Heimer, Y M, Riklis, E
Format: Artigo
Language:Inglês
Published: 1979
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1161489/
https://ncbi.nlm.nih.gov/pubmed/534483
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