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A Unique Heparin-Binding Domain in the Envelope Protein of the Neuropathogenic PVC-211 Murine Leukemia Virus May Contribute to Its Brain Capillary Endothelial Cell Tropism

Previous studies from our laboratory demonstrated that PVC-211 murine leukemia virus (MuLV), a neuropathogenic variant of Friend MuLV (F-MuLV), had undergone genetic changes which allowed it to efficiently infect rat brain capillary endothelial cells (BCEC) in vivo and in vitro. Two amino acid chang...

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Hlavní autoři: Jinno-Oue, Atsushi, Oue, Miho, Ruscetti, Sandra K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC116140/
https://ncbi.nlm.nih.gov/pubmed/11711634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12439-12445.2001
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