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Production and Characterization of Monoclonal Antibodies Specific for a Conserved Epitope within Hepatitis C Virus Hypervariable Region 1

Frequent mutations in hypervariable region 1 (HVR1) of the main envelope protein of hepatitis C virus (HCV) is a major mechanism of persistence by escaping the host immune recognition. HVR1 contains an epitope eliciting neutralizing antibodies. This study was aimed to prepare broadly cross-reacting,...

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Detalhes bibliográficos
Main Authors: Li, Chengyao, Candotti, Daniel, Allain, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116137/
https://ncbi.nlm.nih.gov/pubmed/11711631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12412-12420.2001
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