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Altered Cellular mRNA Levels in Human Cytomegalovirus-Infected Fibroblasts: Viral Block to the Accumulation of Antiviral mRNAs

The effect of human cytomegalovirus (HCMV) infection on cellular mRNA accumulation was analyzed by gene chip technology. During a 48-h time course after infection of human diploid fibroblasts, 1,425 cellular mRNAs were found to be up-regulated or down-regulated by threefold or greater in at least tw...

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Bibliografiske detaljer
Main Authors: Browne, Edward P., Wing, Bret, Coleman, David, Shenk, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC116128/
https://ncbi.nlm.nih.gov/pubmed/11711622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12319-12330.2001
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