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Inhibition of human alkaline phosphatases by vanadate.

Orthovanadate was shown to be a potent competitive inhibitor (Ki less than 1 microM) of purified alkaline phosphatase from human liver, intestine of kidney. Inhibition was reversed and full enzymic activity restored in the presence of 1mM-adrenaline. Phosphate and vanadate competed for the same bind...

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Autori principali: Seargeant, L E, Stinson, R A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1161148/
https://ncbi.nlm.nih.gov/pubmed/486156
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