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The Major Human Immunodeficiency Virus Type 2 (HIV-2) Packaging Signal Is Present on All HIV-2 RNA Species: Cotranslational RNA Encapsidation and Limitation of Gag Protein Confer Specificity

Deletion of a region of the human immunodeficiency virus type 2 (HIV-2) 5′ leader RNA reduces genomic RNA encapsidation to about 5% that of wild-type virus with no defect in viral protein production but severely limits virus spread in Jurkat T cells, indicating that this region contains a major cis-...

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Udgivet i:J Virol
Principais autores: Griffin, Stephen D. C., Allen, Jane F., Lever, Andrew M. L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11711596/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.24.12058-12069.2001
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