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The equine periodic paralysis Na+ channel mutation alters molecular transitions between the open and inactivated states.

1. The Na+ channel mutation associated with equine hyperkalaemic periodic paralysis (HPP) affects a highly conserved phenylalanine residue in an unexplored region of the alpha-subunit. This mutation was introduced into the rat skeletal muscle Na+ channel gene at the corresponding location (i.e. F141...

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Detalhes bibliográficos
Main Authors: Hanna, W J, Tsushima, R G, Sah, R, McCutcheon, L J, Marban, E, Backx, P H
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160989/
https://ncbi.nlm.nih.gov/pubmed/8961180
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