cis Expression of DC-SIGN Allows for More Efficient Entry of Human and Simian Immunodeficiency Viruses via CD4 and a Coreceptor

DC-SIGN is a C-type lectin expressed on dendritic cells and restricted macrophage populations in vivo that binds gp120 and acts in trans to enable efficient infection of T cells by human immunodeficiency virus type 1 (HIV-1). We report here that DC-SIGN, when expressed in cis with CD4 and coreceptor...

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Detalhes bibliográficos
Main Authors: Lee, Benhur, Leslie, George, Soilleux, Elizabeth, O'Doherty, Una, Baik, Sarah, Levroney, Ernest, Flummerfelt, Karen, Swiggard, William, Coleman, Nicholas, Malim, Michael, Doms, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116098/
https://ncbi.nlm.nih.gov/pubmed/11711593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.12028-12038.2001
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