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Functional Mapping of the DNA Binding Domain of Bovine Papillomavirus E1 Protein

Bovine papillomavirus type 1 (BPV-1) requires viral proteins E1 and E2 for efficient DNA replication in host cells. E1 functions at the BPV origin as an ATP-dependent helicase during replication initiation. Previously, we used alanine mutagenesis to identify two hydrophilic regions of the E1 DNA bin...

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Bibliografiske detaljer
Main Authors: West, Michael, Flanery, David, Woytek, Kelly, Rangasamy, Dhandapani, Wilson, Van G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC116090/
https://ncbi.nlm.nih.gov/pubmed/11711585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.24.11948-11960.2001
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