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Human TFIIIC Relieves Chromatin-Mediated Repression of RNA Polymerase III Transcription and Contains an Intrinsic Histone Acetyltransferase Activity

Human TFIIIC is a multisubunit factor that is essential for transcription by RNA polymerase III on tRNA and virus-associated RNA genes and initiates preinitiation complex assembly by direct recognition of promoter elements. We show that highly purified TFIIIC, at concentrations above those sufficien...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Kundu, Tapas K., Wang, Zhengxin, Roeder, Robert G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9891093/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.2.1605
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