Characterization of an ultrarapid delayed rectifier potassium channel involved in canine atrial repolarization.

1. Depolarizing pulses positive to 0 mV elicit a transient outward current (Ito) and a sustained 'pedestal' current in canine atrial myocytes. The pedestal current was highly sensitive to 4-aminopyridine (4-AP) and TEA, with 50% inhibitory concentrations (EC50) of 5.3 +/- 0.7 and 307 +/- 2...

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Dettagli Bibliografici
Autori principali: Yue, L, Feng, J, Li, G R, Nattel, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160853/
https://ncbi.nlm.nih.gov/pubmed/8930833
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