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Effect on the indo-1 transient of applying Ca2+ channel blocker for a single beat in voltage-clamped guinea-pig cardiac myocytes.

1. We used rapid solution changes to investigate the mechanisms which trigger Ca2+ release from the sarcoplasmic reticulum (SR) in guinea-pig ventricular myocytes. We patch-clamped myocytes at 36 degrees C and used indo-1 to monitor intracellular Ca2+. Before each test pulse, we established a standa...

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Detalhes bibliográficos
Main Authors: Levi, A J, Li, J, Spitzer, K W, Bridge, J H
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160667/
https://ncbi.nlm.nih.gov/pubmed/8865064
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