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The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals

Protein nuclear import is generally mediated by basic nuclear localization signals (NLSs) that serve as targets for the importin α (Imp α) NLS receptor. Imp α is in turn bound by importin β (Imp β), which targets the resultant protein complex to the nucleus. Here, we report that the arginine-rich NL...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Truant, Ray, Cullen, Bryan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9891055/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.2.1210
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