Rapid down-regulation of substance P binding to guinea-pig pancreatic acinar cells during homologous desensitization.

Binding of 125I-labelled peptides, cytoplasmic Ca2+ concentration ([Ca2+]i) and amylase release were studied in guinea-pig pancreatic acinar cells during exposure to substance P (SP), and cholecystokinin octapeptide (CCK-8). Pre-incubation of cells at 22 degrees C with 0.03 nM to 1 microM SP for 10...

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Detalles Bibliográficos
Main Authors: Sjödin, L, Viitanen, E, Gylfe, E
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160419/
https://ncbi.nlm.nih.gov/pubmed/7519262
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