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GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences

Caspases and granzyme B are proteases that share the primary specificity to cleave at the carboxyl terminal of aspartate residues in their substrates. Both, caspases and granzyme B are enzymes that are involved in fundamental cellular processes and play a central role in apoptotic cell death. Althou...

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Bibliografske podrobnosti
Main Authors: Backes, Christina, Kuentzer, Jan, Lenhof, Hans-Peter, Comtesse, Nicole, Meese, Eckart
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160194/
https://ncbi.nlm.nih.gov/pubmed/15980455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki433
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