Single-Dose Mucosal Immunization with Biodegradable Microparticles Containing a Schistosoma mansoni Antigen

The purpose of this work was to assess the immunogenicity of a single nasal or oral administration of recombinant 28-kDa glutathione S-transferase of Schistosoma mansoni (rSm28GST) entrapped by poly(lactide-co-glycolide) (PLG)- or polycaprolactone (PCL)-biodegradable microparticles. Whatever the pol...

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Autori principali: Baras, Benoît, Benoit, Marie-Ange, Dupré, Loïc, Poulain-Godefroy, Odile, Schacht, Anne-Marie, Capron, André, Gillard, Jean, Riveau, Gilles
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC116018/
https://ncbi.nlm.nih.gov/pubmed/10225935
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