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Vaccination of Guinea Pigs with Nutritionally Impaired Avirulent Mutants of Mycobacterium bovis Protects against Tuberculosis

Four nutritionally impaired strains of Mycobacterium bovis produced by illegitimate recombination were tested for their ability to protect guinea pigs against intratracheal challenge with virulent M. bovis. All four strains and M. bovis BCG induced significant levels of protection as measured by the...

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Detalhes bibliográficos
Main Authors: de Lisle, Geoffrey W., Wilson, Theresa, Collins, Desmond M., Buddle, Bryce M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116014/
https://ncbi.nlm.nih.gov/pubmed/10225931
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