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Vaccination of Guinea Pigs with Nutritionally Impaired Avirulent Mutants of Mycobacterium bovis Protects against Tuberculosis

Four nutritionally impaired strains of Mycobacterium bovis produced by illegitimate recombination were tested for their ability to protect guinea pigs against intratracheal challenge with virulent M. bovis. All four strains and M. bovis BCG induced significant levels of protection as measured by the...

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Main Authors: de Lisle, Geoffrey W., Wilson, Theresa, Collins, Desmond M., Buddle, Bryce M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC116014/
https://ncbi.nlm.nih.gov/pubmed/10225931
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