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Inhibition of ATP-activated current by zinc in dorsal root ganglion neurones of bullfrog.

1. The effect of Zn2+ on ATP-activated current was studied in bullfrog dorsal root ganglion (DRG) neurones using the whole-cell patch-clamp technique. 2. Zn2+ (2-800 microM) inhibited current activated by submaximal concentrations of ATP. The Zn2+ concentration that produced 50% inhibition (IC50) of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, C, Peoples, R W, Weight, F F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160042/
https://ncbi.nlm.nih.gov/pubmed/9457642
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