Membrane Permeabilization by Thrombin-Induced Platelet Microbicidal Protein 1 Is Modulated by Transmembrane Voltage Polarity and Magnitude

Thrombin-induced platelet microbicidal protein 1 (tPMP-1) is a small, cationic peptide generated from rabbit platelets when they are exposed to thrombin in vitro. It has potent microbicidal activity against a broad spectrum of bacterial and fungal pathogens, including Staphylococcus aureus. Previous...

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Bibliographic Details
Main Authors: Koo, Su-Pin, Bayer, Arnold S., Kagan, Bruce L., Yeaman, Michael R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC115993/
https://ncbi.nlm.nih.gov/pubmed/10225910
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