Effects of development and thyroid hormone on K+ currents and K+ channel gene expression in rat ventricle.

1. In rat heart, three K+ channel genes that encode inactivating transient outward (ITO)-like currents are expressed. During development the predominant K+ channel mRNA species switches from Kv1.4 to Kv4.2 and Kv4.3. However, no functional correlate of this isoform switch has been reported. We inves...

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Autori principali: Wickenden, A D, Kaprielian, R, Parker, T G, Jones, O T, Backx, P H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159909/
https://ncbi.nlm.nih.gov/pubmed/9365903
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