Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes.

1. We examined [Ca2+]i and L-type Ca2+ channel current (ICa) in single cardiac myocytes to determine how the intracellular protein phospholamban (PLB) influences excitation-contraction (E-C) coupling in heart. Wild type (WT) and PLB-deficient (KO) mice were used. Cells were patch clamped in whole-ce...

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Hlavní autoři: Santana, L F, Kranias, E G, Lederer, W J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159883/
https://ncbi.nlm.nih.gov/pubmed/9288671
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