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P-glycoprotein is not a swelling-activated Cl- channel; possible role as a Cl- channel regulator.

1. The whole-cell configuration of the patch-clamp technique was used to determine if P-glycoprotein (Pgp) is a swelling-activated Cl- channel. 2. Hamster pgp1 cDNA was transfected into a mouse fibroblast cell line resulting in expression of functional Pgp in the plasma membrane. This cell line was...

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Detalhes bibliográficos
Main Authors: Vanoye, C G, Altenberg, G A, Reuss, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159546/
https://ncbi.nlm.nih.gov/pubmed/9263907
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