Evaluation of Accumulation of Hepatitis C Virus Mutations in a Chronically Infected Chimpanzee: Comparison of the Core, E1, HVR1, and NS5b Regions

Four hepatitis C virus genome regions (the core, E1, HVR1, and NS5b) were amplified and sequenced from yearly samples obtained from a chronically infected chimpanzee over a 12-year span. Nucleotide substitutions were found to accumulate in the core, E1, and HVR1 regions during the course of chronic...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Lu, Ling, Nakano, Tatsunori, Orito, Etsuro, Mizokami, Masashi, Robertson, Betty H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Recombination and Evolution
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11222726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.6.3004-3009.2001
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