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Intrarenal cells, not bone marrow–derived cells, are the major source for regeneration in postischemic kidney

Ischemic injury to the kidney produces acute tubular necrosis and apoptosis followed by tubular regeneration and recovery of renal function. Although mitotic cells are present in the tubules of postischemic kidneys, the origins of the proliferating cells are not known. Bone marrow cells (BMCs) can d...

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Autori principali: Lin, Fangming, Moran, Ashley, Igarashi, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159127/
https://ncbi.nlm.nih.gov/pubmed/16007252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23015
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