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Time-dependent current decline in cyclic GMP-gated bovine channels caused by point mutations in the pore region expressed in Xenopus oocytes.

1. Amino acids with a charged or a polar residue in the putative pore region, between lysine 346 and glutamate 372 of the alpha-subunit of the cGMP-gated channel from bovine rods were mutated to a different amino acid. The mRNA encoding for the wild-type, i.e. the alpha-subunit, or mutant channels w...

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Detalhes bibliográficos
Main Authors: Bucossi, G, Eismann, E, Sesti, F, Nizzari, M, Seri, M, Kaupp, U B, Torre, V
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158926/
https://ncbi.nlm.nih.gov/pubmed/8782105
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