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A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells.

1. Single cells were isolated from the sinus node region of rabbits (2 days old to adult) to study the age-dependent contribution of the sodium current (iNa) to pacemaker activity. 2. Experiments were conducted in 50 mM Na(+)-Ca(2+)-free solution. All newborn cells (2-19 days) exhibited a TTX-sensit...

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Main Authors: Baruscotti, M, DiFrancesco, D, Robinson, R B
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158857/
https://ncbi.nlm.nih.gov/pubmed/8730579
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