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Control of ion flux and selectivity by negatively charged residues in the outer mouth of rat sodium channels.

1. The sodium channel has a ring of negatively charged amino acids on its external face. This common structural feature of cation-selective channels has been proposed to optimize conduction by electrostatic attraction of permeant cations into the channel mouth. We tested this idea by mutagenesis of...

詳細記述

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書誌詳細
主要な著者: Chiamvimonvat, N, Pérez-García, M T, Tomaselli, G F, Marban, E
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158758/
https://ncbi.nlm.nih.gov/pubmed/9011621
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