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High affinity binding of anti-oestrogen to the chick liver nuclear oestrogen receptor
Tamoxifen is a potent inhibitor of specific oestrogen-induced yolk protein synthesis by chicken liver. The oestradiol receptor in salt extracts of liver nuclei from oestrogen-treated chicks has a K(d) for oestradiol of 0.7±0.2nm. Tamoxifen and its metabolite, monohydroxytamoxifen, compete for bindin...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1982
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1158596/ https://ncbi.nlm.nih.gov/pubmed/7150249 |
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