Effects of 2-mercaptoacetate in isolated liver mitochondria in vitro. Competitive inhibition of 3-hydroxybutyrate dehydrogenase and depression of the beta-oxidation pathway.

The effects of 2-mercaptoacetate on the respiration rates induced by different substrates were studied in vitro in isolated liver mitochondria. With palmitoyl-L-carnitine or 2-oxoglutarate as the substrate, the ADP-stimulated respiration (State 3) was dose-dependently inhibited by 2-mercaptoacetate....

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Hauptverfasser: Bauché, F, Sabourault, D, Giudicelli, Y, Nordmann, J, Nordmann, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158548/
https://ncbi.nlm.nih.gov/pubmed/7126196
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