Spin-trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions isolated hepatocytes and in vivo in the rat.

1. The metabolic activation of carbon tetrachloride to free-radical intermediates is an important step in the sequence of disturbances leading to the acute liver injury produced by this toxic agent. Electron-spin-resonance (e.s.r.) spin-trapping techniques were used to characterize the free-radical...

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Main Authors: Albano, E, Lott, K A, Slater, T F, Stier, A, Symons, M C, Tomasi, A
格式: Artigo
語言:Inglês
出版: 1982
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158389/
https://ncbi.nlm.nih.gov/pubmed/6288023
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