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The effects of lactoyl-pepstatin and the pepsin inhibitor peptide on pig cathepsin D.

Lactoyl-pepstatin (an acylated tetrapeptide) is much more readily soluble in aqueous media than the more common isovaleryl- and acetyl-pepstatins (acylated pentapeptides). However, the K1 value for inhibition of cathepsin D by lactoyl-pepstatin at pH 3.5 is approx. 10(-7) M, some two to three orders...

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Autors principals: Kay, J, Afting, E G, Aoyagi, T, Dunn, B M
Format: Artigo
Idioma:Inglês
Publicat: 1982
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158299/
https://ncbi.nlm.nih.gov/pubmed/7115318
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