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Synthesis and application of chemically reactive proteins by the reversible modification of protein amino groups with exo-cis-3,6-endo-epoxy-4,5-cis-epoxyhexahydrophthalic anhydride.
The reversible reaction of exo-cis-3,6-endo-epoxy-4,5-cis-epoxyhexahydrophthalic anhydride (EEHPA) with free protein amino groups is described. The free protein amino groups of lysozyme can be completely blocked through the reaction of the anhydride EEHPA. The chemically less reactive epoxy groups i...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1982
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1158236/ https://ncbi.nlm.nih.gov/pubmed/7115290 |
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