Evidence that poly(ADP-ribose) polymerase is involved in the loss of NAD from cultured rat liver cells.

Rat hepatocytes cultured from 24h lose 60% of their NAD content. By using the differential response to inhibitors of the two major enzymes that catabolize NAD in mammalian cells, it is shown that poly(ADP-ribose) polymerase is responsible for the loss of NAD. The relevance of this observation to the...

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Bibliographic Details
Main Authors: Paine, A J, Allen, C M, Durkacz, B W, Shall, S
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158142/
https://ncbi.nlm.nih.gov/pubmed/6284133
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