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Role of membrane potential in endothelium-dependent relaxation of guinea-pig coronary arterial smooth muscle.

1. Membrane potential and tension were measured simultaneously in ring segments of main coronary artery of guinea-pigs. The synthetic thromboxane A2 analogue U46619 depolarized the tissues from -58 +/- 2 to -40 +/- 1 mV and increased tension by 12 +/- 1 mN mm-1. Nitric oxide (NO) and Iloprost, the s...

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Main Authors: Parkington, H C, Tonta, M A, Coleman, H A, Tare, M
格式: Artigo
語言:Inglês
出版: 1995
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157908/
https://ncbi.nlm.nih.gov/pubmed/7541469
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