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Effects of intracellular calcium on sodium current density in cultured neonatal rat cardiac myocytes.

1. Na+ channel mRNA levels in the heart can be modulated by changes in intracellular Ca2+ ([Ca2+]i). We have investigated whether this regulation of Na+ channel biosynthesis by cytosolic Ca2+ translates into functional Na+ channels that can be detected electrophysiologically. 2. Whole-cell Na+ curre...

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Detalhes bibliográficos
Main Authors: Chiamvimonvat, N, Kargacin, M E, Clark, R B, Duff, H J
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157846/
https://ncbi.nlm.nih.gov/pubmed/7650605
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