A cysteine-sulfinic acid in peroxiredoxin regulates H(2)O(2)-sensing by the antioxidant Pap1 pathway

The Schizosaccharomyces pombe transcription factor Pap1 regulates antioxidant-gene transcription in response to H(2)O(2). Pap1 activation occurs only at low, but not elevated, H(2)O(2) concentrations that instead strongly trigger the mitogen-activated protein kinase Sty1 pathway. Here, we identify t...

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Detalhes bibliográficos
Main Authors: Vivancos, Ana P., Castillo, Esther A., Biteau, Benoît, Nicot, Carine, Ayté, José, Toledano, Michel B., Hidalgo, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157045/
https://ncbi.nlm.nih.gov/pubmed/15956211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503251102
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