Genetic Deletion of Murine SPRY Domain-Containing SOCS Box Protein 2 (SSB-2) Results in Very Mild Thrombocytopenia

The SSB family is comprised of four highly homologous proteins containing a C-terminal SOCS box motif and a central SPRY domain. No function has yet been ascribed to any member of this family in mammalian species despite a clear role for other SOCS proteins in negative regulation of cytokine signali...

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Detalhes bibliográficos
Main Authors: Masters, S. L., Palmer, K. R., Stevenson, W. S., Metcalf, D., Viney, E. M., Sprigg, N. S., Alexander, W. S., Nicola, N. A., Nicholson, S. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156973/
https://ncbi.nlm.nih.gov/pubmed/15964819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5639-5647.2005
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