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The DNA Damage-Inducible UbL-UbA Protein Ddi1 Participates in Mec1-Mediated Degradation of Ho Endonuclease

Ho endonuclease initiates a mating type switch by making a double-strand break at the mating type locus, MAT. Ho is marked by phosphorylation for rapid destruction by functions of the DNA damage response, MEC1, RAD9, and CHK1. Phosphorylated Ho is recruited for ubiquitylation via the SCF ubiquitin l...

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Detalhes bibliográficos
Main Authors: Kaplun, Ludmila, Tzirkin, Regina, Bakhrat, Anya, Shabek, Nitzan, Ivantsiv, Yelena, Raveh, Dina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156969/
https://ncbi.nlm.nih.gov/pubmed/15964793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5355-5362.2005
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