Activation of muscarinic K+ current in guinea-pig atrial myocytes by sphingosine-1-phosphate.

1. Activation of muscarinic K+ current (IK(ACh)) by sphingosine-1-phosphate (Sph-1-P) was studied in isolated cultured guinea-pig atrial myocytes using whole-cell voltage clamp. 2. Sph-1-P caused activation of IK(ACh) with an EC50 of 1.2 nM. The maximal current that could be activated by Sph-1-P amo...

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Bibliographic Details
Main Authors: Bünemann, M, Brandts, B, zu Heringdorf, D M, van Koppen, C J, Jakobs, K H, Pott, L
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156840/
https://ncbi.nlm.nih.gov/pubmed/8788935
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