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Inhibition by cyanate of the processing of lysosomal enzymes.

In cultured human fibroblasts, maturation of the lysosomal enzymes beta-hexosaminidase and cathepsin D is inhibited by 10 mM-potassium cyanate. In cells treated with cyanate the two enzymes accumulate in precursor forms. The location of the accumulated precursor is probably non-lysosomal; in fractio...

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Bibliografski detalji
Glavni autori: Hasilik, A, Pohlmann, R, von Figura, K
Format: Artigo
Jezik:Inglês
Izdano: 1983
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1154292/
https://ncbi.nlm.nih.gov/pubmed/6223628
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