Selective uptake of alloxan by pancreatic B-cells

Alloxan rapidly binds to or accumulates in pancreatic B-cells as distinct from non-B-cells. The selective uptake of this cytotoxic agent by the insulin-producing B-cells might account for its well-known diabetogenic effect.

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Detalhes bibliográficos
Main Authors: Gorus, Frans K., Malaisse, Willy J., Pipeleers, Daniël G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Metabolism, Regulation and Control Processes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153992/
https://ncbi.nlm.nih.gov/pubmed/6760861
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