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Cell intrinsic alterations underlie hematopoietic stem cell aging

Loss of immune function and an increased incidence of myeloid leukemia are two of the most clinically significant consequences of aging of the hematopoietic system. To better understand the mechanisms underlying hematopoietic aging, we evaluated the cell intrinsic functional and molecular properties...

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Autores principales: Rossi, Derrick J., Bryder, David, Zahn, Jacob M., Ahlenius, Henrik, Sonu, Rebecca, Wagers, Amy J., Weissman, Irving L.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153718/
https://ncbi.nlm.nih.gov/pubmed/15967997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503280102
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