Cell intrinsic alterations underlie hematopoietic stem cell aging

Loss of immune function and an increased incidence of myeloid leukemia are two of the most clinically significant consequences of aging of the hematopoietic system. To better understand the mechanisms underlying hematopoietic aging, we evaluated the cell intrinsic functional and molecular properties...

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Bibliografiske detaljer
Main Authors: Rossi, Derrick J., Bryder, David, Zahn, Jacob M., Ahlenius, Henrik, Sonu, Rebecca, Wagers, Amy J., Weissman, Irving L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153718/
https://ncbi.nlm.nih.gov/pubmed/15967997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503280102
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