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A mass-spectrometric investigation of the mechanism of the semisynthetic transformation of pig insulin into an ester of insulin of human sequence.

In the trypsin-mediated semisynthetic transformation of pig insulin into an ester of insulin of human sequence, the B30 alanine residue of the pig hormone is replaced by an ester of threonine. The mechanism of this reaction was investigated by carrying out the transformation in a medium containing w...

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Dettagli Bibliografici
Autori principali: Rose, K, Gladstone, J, Offord, R E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1984
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153609/
https://ncbi.nlm.nih.gov/pubmed/6378184
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