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Inhibition of gluconeogenesis in rat liver by lipoic acid. Evidence for more than one site of action.
Hepatocytes obtained from starved rats were incubated in oxygenated Krebs bicarbonate buffer containing 2% defatted bovine serum albumin. DL-alpha-Lipoic (dithio-octanoic) acid (1.0 mM) caused striking reductions in hepatic glucose output in the presence of each of the following substrates: pyruvate...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1984
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1153543/ https://ncbi.nlm.nih.gov/pubmed/6430273 |
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