Regulation of insulin secretion by energy metabolism in pancreatic B-cell mitochondria. Studies with a non-metabolizable leucine analogue.

In mouse pancreatic islets the kinetics of insulin secretion and O2 uptake in response to the non-metabolizable leucine analogue (+/-)-BCH (2-endo- aminonorbornane -2-carboxylic acid) were compared. In addition, the fuel-mobilizing effect of (+/-)-BCH was studied with a mitochondrial fraction from i...

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Autores principales: Panten, U, Zielmann, S, Langer, J, Zünkler, B J, Lenzen, S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1984
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153464/
https://ncbi.nlm.nih.gov/pubmed/6372787
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