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Mechanism of hexachlorobenzene-induced porphyria in rats. Effect of phenobarbitone pretreatment.

The effect of a pretreatment with phenobarbitone (PB) on the porphyrinogenic action exerted by hexachlorobenzene (HCB) was examined in female rats. Kinetic studies of enzyme function after HCB poisoning showed that porphyrinogen carboxy-lyase was the only enzyme of haem biosynthesis that markedly lo...

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Autors principals: Wainstok de Calmanovici, R, Ríos de Molina, M C, Taira de Yamasato, M C, Tomio, J M, San Martin de Viale, L C
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153403/
https://ncbi.nlm.nih.gov/pubmed/6721832
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